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+                西柚对药物的影响
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+            Nov 15, 2024
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+    <p>西柚，橙子之类中的呋喃香豆素会抑制肝脏中  CYP3A4 酶的活性，经肝脏代谢的药物，正常是肝脏中的酶在发挥作用，CYP3A4 酶就是其中一种，吃药的同时又吃了西柚相当于无形中增加了药物剂量，曾经有人吃硝苯地平的同时，喝了大概 500mL 的西柚汁，结果血压迅速下降导致了危险。<br>除此之外这种酶参与了现今使用近半数药物的代谢，总体来说，呋喃香豆素可以使药物以 2～10 倍的量进入血液，目前已知的，有超过 85 种药物会受到西柚的影响，但药物种类实在太多了，很难找到会受西柚影响的完整药物名单。最稳妥的方案还是吃药的时候别他妈吃西柚了</p>
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