From 3d41b57ed78a90e3429c9c1b48b3b230e6cc382f Mon Sep 17 00:00:00 2001 From: i-shm Date: Thu, 20 Aug 2026 03:29:17 +0000 Subject: deploy: 4b5670cdf460609083bc18f078a3da6275f0fd57 --- .../index.html" | 2 +- search.xml | 344 ++++++++++----------- 2 files changed, 173 insertions(+), 173 deletions(-) diff --git "a/2026/08/20/\346\210\277\351\242\244\345\277\203\347\224\265\345\233\276\350\247\243\346\236\220/index.html" "b/2026/08/20/\346\210\277\351\242\244\345\277\203\347\224\265\345\233\276\350\247\243\346\236\220/index.html" index 41b2b0db..c1795b28 100644 --- "a/2026/08/20/\346\210\277\351\242\244\345\277\203\347\224\265\345\233\276\350\247\243\346\236\220/index.html" +++ "b/2026/08/20/\346\210\277\351\242\244\345\277\203\347\224\265\345\233\276\350\247\243\346\236\220/index.html" @@ -207,7 +207,7 @@

下图为教学示意，不是患者原始心电图的重建，也不用于自动诊断。点击“播放动画”后，扫描线会沿时间轴移动；点击观察点按钮可以突出相应标注。动画用于说明“连续记录”和“节律间期”的概念，不代表真实心电设备的采样参数。

连续节律示意：窦性心律与房颤

教学示意｜动画表示时间轴移动，不代表原始检测记录

ECG SKETCH
diff --git a/search.xml b/search.xml index 6e0ff269..feb82ab5 100644 --- a/search.xml +++ b/search.xml @@ -1130,6 +1130,69 @@ await prisma.$transaction(async tx => {
  • 当指数变为0时，循环结束，返回ret

    • 这个实现的优点是它可以在对数时间内计算出幂运算，而且每次循环只需要4次乘法。这比标准的二分快速幂算法需要的乘法次数更少。

    +]]> + + Technique + + + + OCaml News 2024-1 + /2024/01/08/OCaml-News-2024-1/ + News + +

    Videos

    + +

    Blogs

    + +

    Highlighted Projects

    + +

    New Releases

    + ]]>     Technique @@ -1208,69 +1271,6 @@ await prisma.$transaction(async tx => {
  • [ANN] New release of Menhir (20231231)
    • -]]> - - Technique - -     - - OCaml News 2024-1 - /2024/01/08/OCaml-News-2024-1/ - News - -

    Videos

    - -

    Blogs

    - -

    Highlighted Projects

    - -

    New Releases

    - ]]>     Technique @@ -1419,79 +1419,6 @@ await prisma.$transaction(async tx => {

    [ANN] Docfd: TUI multiline fuzzy document finder 2.2.0

    -]]> - - Technique - -     - - OCaml News 2024-5 - /2024/06/27/OCaml-News-2024-5/ - 语言的发展 - -

    新消息

    - -

    有价值的文章

    - -

    有趣的项目

    - ]]>     Technique @@ -1663,6 +1590,79 @@ await prisma.$transaction(async tx => {

    llama: A library for building software-defined modular synthesizers in a declarative style.

    +]]> + + Technique + +     + + OCaml News 2024-5 + /2024/06/27/OCaml-News-2024-5/ + 语言的发展 + +

    新消息

    + +

    有价值的文章

    + +

    有趣的项目

    + ]]>     Technique @@ -2110,28 +2110,6 @@ A relation table (also sometimes called a JOIN, link or pi Technique     - - Radiographic Absence of the Left Humeral Head - /2023/10/25/Radiographic-Absence-of-the-Left-Humeral-Head/ - A 67-year-old man with thoracolumbar scoliosis, poor mobility, and history of frequent falls presented to the emergency department with 2 months of left shoulder pain, stiffness and reduced range of motion, and numbness and paresthesias in his left upper extremity.

    -

    Ten years prior to presentation, he underwent surgical decompression for syringomyelia.

    -

    A magnetic resonance imaging (MRI) scan of his cervical and thoracic spine performed 2 years prior to presentation revealed a recurrent syrinx extending from Cl C1 to T11, which was not resected because it did not cause symptoms at that time.

    -

    On physical examination, he had mild tenderness to palpation and reduced range of motion of the left shoulder with abduction and flexion limited to 120° (normal range of motion, 180°).

    -

    The left scapular muscles were atrophic, and pain and temperature sensation were reduced in his proximal left arm, and dorsal aspect of his left shoulder.

    -

    His complete blood cell count, serum glucose levels, C-reactive protein levels, and erythrocyte sedimentation rate were normal.

    -

    Results of tests for rheumatoid factor and antinuclear antibody were negative.

    -

    Left shoulder radiograph showed complete absence of the left humeral head and a well-demarcated smooth osseous margin of the proximal humerus with associated soft tissue swelling and periarticular calcification.

    -

    A chest radiograph taken 2 years prior revealed a normal left shoulder joint. The patient was hospitalized for further evaluation and treatment.

    - -

    这里提到了一种罕见的进展性疾病, 叫Charcot肩, 是一种神经性关节病变，特点是关节迅速被破坏和相关软组织肿胀。患者通常表现为肩部逐渐增大的肿胀，可能伴有疼痛或无痛，肩部无力和活动范围减少。
    -大约80%的Charcot肩患者有脊髓空洞症, 表现为脊髓中的液体充满腔体

    -]]>     - - Medicine - -     Repository pattern in Typescript /2025/02/19/Repository-pattern-in-Typescript/ @@ -2171,6 +2149,28 @@ A relation table (also sometimes called a JOIN, link or pi Technique + + Radiographic Absence of the Left Humeral Head + /2023/10/25/Radiographic-Absence-of-the-Left-Humeral-Head/ + A 67-year-old man with thoracolumbar scoliosis, poor mobility, and history of frequent falls presented to the emergency department with 2 months of left shoulder pain, stiffness and reduced range of motion, and numbness and paresthesias in his left upper extremity.

    +

    Ten years prior to presentation, he underwent surgical decompression for syringomyelia.

    +

    A magnetic resonance imaging (MRI) scan of his cervical and thoracic spine performed 2 years prior to presentation revealed a recurrent syrinx extending from Cl C1 to T11, which was not resected because it did not cause symptoms at that time.

    +

    On physical examination, he had mild tenderness to palpation and reduced range of motion of the left shoulder with abduction and flexion limited to 120° (normal range of motion, 180°).

    +

    The left scapular muscles were atrophic, and pain and temperature sensation were reduced in his proximal left arm, and dorsal aspect of his left shoulder.

    +

    His complete blood cell count, serum glucose levels, C-reactive protein levels, and erythrocyte sedimentation rate were normal.

    +

    Results of tests for rheumatoid factor and antinuclear antibody were negative.

    +

    Left shoulder radiograph showed complete absence of the left humeral head and a well-demarcated smooth osseous margin of the proximal humerus with associated soft tissue swelling and periarticular calcification.

    +

    A chest radiograph taken 2 years prior revealed a normal left shoulder joint. The patient was hospitalized for further evaluation and treatment.

    + +

    这里提到了一种罕见的进展性疾病, 叫Charcot肩, 是一种神经性关节病变，特点是关节迅速被破坏和相关软组织肿胀。患者通常表现为肩部逐渐增大的肿胀，可能伴有疼痛或无痛，肩部无力和活动范围减少。
    +大约80%的Charcot肩患者有脊髓空洞症, 表现为脊髓中的液体充满腔体

    +]]>     + + Medicine + +     Rescript and React Native /2024/01/22/Rescript-React-Native/ @@ -2491,6 +2491,19 @@ A relation table (also sometimes called a JOIN, link or pi Technique + + TSOPT 检查 + /2025/12/29/TSOPT-%E6%A3%80%E6%9F%A5/ + T-SPOT检查，其全称为T-SPOT.TB，是一种用于检测结核分枝杆菌感染的体外诊断血液检测技术。该方法属于一类被称为γ-干扰素释放试验（Interferon Gamma Release Assay, IGRA）的检测手段，旨在辅助医生诊断个体是否存在结核菌感染，包括活动性结核病和潜伏性结-核感染。此项检测并非直接寻找病原体，而是通过评估人体免疫系统对结核菌特定抗原的反应来做出间接判断，因此，其结果需要结合临床风险评估、影像学检查及其他医疗诊断信息进行综合解读。

    +

    该检测的核心原理在于测量外周血中效应T淋巴细胞的功能。具体而言，检测过程中会分离患者血液中的单个核细胞，并在体外用两种结核分枝杆菌特异性抗原——早期分泌性抗原靶6（ESAT-6）和培养滤液蛋白10（CFP-10）——对其进行刺激。这两种蛋白由结核分枝杆菌表达，但绝大多数非结核分枝杆菌以及目前使用的所有卡介苗（BCG疫苗）菌株均不表达，这使得T-SPOT.TB检测相比于传统的结核菌素皮肤试验（TST）具有更高的特异性，能有效避免因卡介苗接种史或大多数非结核分枝杆菌感染而导致的假阳性结果。

    +

    如果受检者的免疫系统曾经接触过结核分枝杆菌，其血液中会存在能够识别这些特异性抗原的效应T细胞。当这些T细胞在体外再次遇到ESAT-6和CFP-10时，会被激活并释放γ-干扰素（IFN-γ）。T-SPOT.TB检测利用一种名为酶联免疫斑点（ELISPOT）的技术，在微孔板中捕获并可视化这些由单个T细胞释放的γ-干扰素，形成可见的“斑点”。通过计数这些斑点的数量，可以量化对结核菌抗原敏感的T细胞的丰度，从而判断免疫系统是否对结核菌存在记忆反应。

    +

    检测结果通常以阳性、阴性或临界（可疑）的形式报告。阳性结果表明受检者很可能感染了结核分枝杆菌；阴性结果则意味着未检测到对结核菌的免疫反应，提示可能没有感染；而临界结果则表示无法明确判断，可能建议重新进行检测或结合其他诊断方法进一步评估。由于其操作的标准化和对特定抗原的依赖，T-SPOT.TB被认为是一种重要的结核病辅助诊断工具，尤其适用于那些因免疫抑制状态（如HIV感染者或长期使用免疫抑制剂的患者）而导致结核菌素皮肤试验结果不可靠的人群。

    +

    参考文献

    +]]>     + + Medicine + +     TDD 和 DDD 的一些小想法 /2025/03/20/TDD-%E5%92%8C-DDD-%E7%9A%84%E4%B8%80%E4%BA%9B%E5%B0%8F%E6%83%B3%E6%B3%95/ @@ -2531,19 +2544,6 @@ A relation table (also sometimes called a JOIN, link or pi Technique - - TSOPT 检查 - /2025/12/29/TSOPT-%E6%A3%80%E6%9F%A5/ - T-SPOT检查，其全称为T-SPOT.TB，是一种用于检测结核分枝杆菌感染的体外诊断血液检测技术。该方法属于一类被称为γ-干扰素释放试验（Interferon Gamma Release Assay, IGRA）的检测手段，旨在辅助医生诊断个体是否存在结核菌感染，包括活动性结核病和潜伏性结-核感染。此项检测并非直接寻找病原体，而是通过评估人体免疫系统对结核菌特定抗原的反应来做出间接判断，因此，其结果需要结合临床风险评估、影像学检查及其他医疗诊断信息进行综合解读。

    -

    该检测的核心原理在于测量外周血中效应T淋巴细胞的功能。具体而言，检测过程中会分离患者血液中的单个核细胞，并在体外用两种结核分枝杆菌特异性抗原——早期分泌性抗原靶6（ESAT-6）和培养滤液蛋白10（CFP-10）——对其进行刺激。这两种蛋白由结核分枝杆菌表达，但绝大多数非结核分枝杆菌以及目前使用的所有卡介苗（BCG疫苗）菌株均不表达，这使得T-SPOT.TB检测相比于传统的结核菌素皮肤试验（TST）具有更高的特异性，能有效避免因卡介苗接种史或大多数非结核分枝杆菌感染而导致的假阳性结果。

    -

    如果受检者的免疫系统曾经接触过结核分枝杆菌，其血液中会存在能够识别这些特异性抗原的效应T细胞。当这些T细胞在体外再次遇到ESAT-6和CFP-10时，会被激活并释放γ-干扰素（IFN-γ）。T-SPOT.TB检测利用一种名为酶联免疫斑点（ELISPOT）的技术，在微孔板中捕获并可视化这些由单个T细胞释放的γ-干扰素，形成可见的“斑点”。通过计数这些斑点的数量，可以量化对结核菌抗原敏感的T细胞的丰度，从而判断免疫系统是否对结核菌存在记忆反应。

    -

    检测结果通常以阳性、阴性或临界（可疑）的形式报告。阳性结果表明受检者很可能感染了结核分枝杆菌；阴性结果则意味着未检测到对结核菌的免疫反应，提示可能没有感染；而临界结果则表示无法明确判断，可能建议重新进行检测或结合其他诊断方法进一步评估。由于其操作的标准化和对特定抗原的依赖，T-SPOT.TB被认为是一种重要的结核病辅助诊断工具，尤其适用于那些因免疫抑制状态（如HIV感染者或长期使用免疫抑制剂的患者）而导致结核菌素皮肤试验结果不可靠的人群。

    -

    参考文献

    -]]>     - - Medicine - -     他克莫司在心衰合并COPD晚期患者淤积性皮炎中的姑息治疗可行性报告 /2026/03/06/Tacrolimus-for-Stasis-Dermatitis-in-Palliative-Heart-Failure-and-COPD/ @@ -6236,7 +6236,7 @@ NestJS 依赖其底层 HTTP 适配器（默认为 Express）来解析传入的

    下图为教学示意，不是患者原始心电图的重建，也不用于自动诊断。点击“播放动画”后，扫描线会沿时间轴移动；点击观察点按钮可以突出相应标注。动画用于说明“连续记录”和“节律间期”的概念，不代表真实心电设备的采样参数。

    连续节律示意：窦性心律与房颤

    教学示意｜动画表示时间轴移动，不代表原始检测记录

    ECG SKETCH
    -- cgit v1.2.3